Involvement of nitric oxide and its up/down stream molecules in the immunity against parasitic infections

Brazilian Journal of Infectious Diseases

Nahrevanian, Hossein¹ 

[1] Pasteur Institute of Iran, Tehran, Iran

关键词: iNOS;    nitric oxide;    NO;    immunity;    helminth;    parasite;    Protozoa;   

DOI  :  10.1590/S1413-86702009000600010

来源: Contexto

【 摘 要 】

Nitric oxide (NO) is a potent mediator with diverse roles in regulating cellular functions and signaling pathways. The NO synthase (NOS) enzyme family consists of three major isoforms, which convey variety of messages between cells, including signals for vasorelaxation, neurotransmission and cytotoxicity. This family of enzymes are generally classified as neuronal NOS (nNOS), endothelial NOS (eNOS) and inducible NOS (iNOS). Increased levels of NO are induced from iNOS during infection; while eNOS and nNOS may be produced at the baseline in normal conditions. An association of some

【 授权许可】

CC BY-NC-ND