New Topics in Vasopressin Receptors and Approach to Novel Drugs: Effects of Vasopressin Receptor on Regulations of Hormone Secretion and Metabolisms of Glucose, Fat, and Protein

Journal of Pharmacological Sciences

Akito Tanoue¹ 

[1] Department of Pharmacology, National Research Institute for Child Health and Development, Japan

关键词: arginine vasopressin;    metabolism;    hormone;    adrenocorticotropic hormone (ACTH);   

DOI  :  10.1254/jphs.08R15FM

学科分类：药学

来源: Nihon Yakuri Gakkai Henshuubu / Japanese Pharmacological Society

【 摘 要 】

References(14)Cited-By(6)The neurohypophyseal peptide [Arg8]-vasopressin (AVP) is involved in diverse functions such as the regulation of body fluid homeostasis, metabolism, and hormone secretion. In this study, we analyzed the functional roles of AVP in hormone release and metabolisms of glucose, fat, and protein in mutant mice lacking the V1a (V1aR-KO) or V1b receptor (V1bR-KO). Our study suggests that antagonists for the receptors could affect the hormone secretions and metabolisms.

【 授权许可】

Unknown