A Retrospective Histopathological Survey on Canine and Feline Liver Diseasesat the University of Tokyo between 2006 and 2012

Journal of Veterinary Medical Science

Koichi OHNO²  Naoki HIROSE¹  Hideyuki KANEMOTO²  James K. CHAMBERS¹  Kazuyuki UCHIDA¹  Hiroyuki NAKAYAMA¹ 

[1] Departments of Veterinary Pathology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113�?8657, Japan;Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo 113�?8657, Japan

关键词: canine;    epidemiology;    feline;    liver disease;    pathology;   

DOI  :  10.1292/jvms.14-0083

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(30)Cited-By(1)To determine the incidence ofhepatic diseases in dogs and cats in Japan, a retrospective study was performed using dataof 463 canine and 71 feline liver biopsies at the Veterinary Medical Center of theUniversity of Tokyo. The most common canine hepatic disease was microvascular dysplasia(MVD) and occupied 29.4% of all diagnoses. This terminology might contain “real�? MVD andprimary portal vein hypoplasia, because these two conditions were difficult to be clearlydistinguished histopathologically. Parenchymal and interstitial hepatitis and primaryhepatic tumors accounted for 23.5% and 21.0% of the diagnoses, respectively. Parenchymaland interstitial hepatitis occupied 34.1% of non-proliferative canine hepatic diseases,while hepatocellular adenoma and carcinoma were 26.6% and 24.5% of proliferative hepaticdiseases, respectively. Breed-specificity was seen in MVD for Yorkshire terrier, Papillonand Toy poodle, in hepatitis for Doberman pinscher and Labrador retriever, incholangiohepatitis for American cocker spaniel, Miniature schnauzer and Pomeranian, inhepatocellular adenoma for Golden retriever and Shiba and in hepatocellular carcinoma forShih Tzu. The most common feline liver disease was parenchymal and interstitial hepatitis(45.1% of all diagnoses). Among feline hepatitis, neutrophilic cholangiohepatitis (23.9%),lymphocytic cholangiohepatitis (14.1%) and chronic hepatitis (5.6%) were recorded. Adultpolycystic liver disease was 5.6%. Among proliferative diseases in the feline liver (11.3%of the all), lymphoma (4.2%) and primary epithelial tumors (4.2%) including hepatocellularcarcinoma, cholangiocellular adenoma and cholangiocellular carcinoma were observed.Hepatic degeneration was 14.1%, and MVD was 12.7%, respectively.

【 授权许可】

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