EFFECTS OF TWO PHYTOTHERAPIC FORMULATIONS CONTAINING Glycine max (L.) MERR ON MALE RAT FERTILITY

Revista de Salud Animal

Bortolini, Carlos Eduardo²  Mattos Rodrigues, Juliano²  Bastos de Mello, Fernanda¹  Boemler Hollenbach, Clarissa²  Braga de Mello, João Roberto²  Hirtz, Lucas² 

[1] UFCSPA - Universidade Federal de Ciências da Saúde de Porto Alegre, Porto Alegre, Brazil;Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil

关键词: soy;    Glycine max;    phytotherapic;    male rats;    fertility;    toxicity;   

DOI  :  

学科分类：兽医学

来源: Centro Nacional de Sanidad Agropecuaria

【 摘 要 】

The present study evaluates the effects of two commercial phytotherapic formulations containing Glycine max (L.) Merr. (Soy) (Phytotherapic A and Phytotherapic B) on Wistar rat fertility. Doses were based on the manufacturer's recommendation and increased in a logarithmic scale. The animals were divided into six experimental groups and a control group, which received distillated water. Three groups were treated with Phytotherapic A and three groups were treated with Phytotherapic B. The doses were: 4.3mg.kg-1.day-1, 21.5 mg.kg-1.day-1 and 43 mg.kg-1.day-1, respectively, for GPA1, GPA2, GPA3, and GPB1, GPB2, GPB3. The males were treated during ninety-one days, before and during the mating. Female Wistar rats were treated before and during the mating, pregnancy and lactation. The total number of spermatozoa, their daily production sperm morphology, histopathology and weight of sexual organs were evaluated. The results showed the interference of the phytotherapic formulations A and B in the total number of spermatozoa and in the sperm morphology in a dose-dependent manner.

【 授权许可】

Unknown