Journal of Veterinary Medical Science | |
Suppressive Effect of Fetal Testes on Development of Fetal Ovaries Transplanted into Adult Males in the Rat | |
Masako YAMAMOTO1  Yasuhiro NAMBA1  Masahiko KUSANAGI1  Kazuyoshi ARISHIMA1  Yasunobu EGUCHI1  | |
关键词: differentiation; fetus; ovary; rat; testis; | |
DOI : 10.1292/jvms.56.1113 | |
学科分类:兽医学 | |
来源: Japanese Society of Veterinary Science | |
【 摘 要 】
References(16)The age-related testicular effect on the ovarian primordia was studied by combined transplantation of fetal testes and ovaries in adult male hosts. First, ovarian primordia of 14-day fetal rats were transplanted into a renal subcapsular position of castrated or intact adult male rats. In both the castrated and the intact hosts, most of the ovarian transplants developed normally with only 3 of them having in part seminiferous tubule-like structures in addition to normal ovarian structure. Second, a 14-day ovary was combined with a fetal testis the age of which varied from 13- to 18-day, and the combination was transplanted. In the combination of a 14-day ovary and a 13-day testis, the results varied in such a way that the ovary or the testis alone developed or otherwise, both gonads developed well. In union with 15- to 18-day testes, the ovaries did not develop, although the testes developed well. These results suggest that the 14-day ovarian primordia have a slight reactiveness to androgens of host rats and that the 13-day fetal testes begin to inhibit the development of the 14-day ovaries co-transplanted with them.
【 授权许可】
Unknown
【 预 览 】
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RO201911300165473ZK.pdf | 2032KB | download |