Pandemic Influenza A (H1N1) Infection in Pregnant and Nonpregnant Women in Spain (2009–2010)

Japanese Journal of Infectious Diseases

Fernando González-Candelas²  Àngela Dominguez²  José M. Mayoral⁸  Pere Godoy²  Olatz Garin²  Miguel Delgado-Rodríguez²  Jesús Castilla²  Jordi Alonso²  Juan C. Galán²  the CIBERESP Cases and Controls in Pandemic Influenza Working Group, Spain¹  Jenaro Astray³  Maretva Baricot²  María Morales Suárez-Varela⁵  Agustín Llopis-González⁵  José M. Quintana²  Sonia Tamames⁶  Vicente Martin²  Ady Castro⁴  Tomás Pumarola⁷ 

[1] Centro de Investigación Biomédica en Red (CIBER) in Epidemiology and Public Health (CIBERESP);Surveillence Branch, Community of Madrid;CIBER Respiratoy Diseases;Unit of Public Health and Environmental Care, Department of Preventive Medicine, University of Valencia;Department of Public Health, Development and Innovation, Junta de Castilla y León;Red Española de Investigación en Patología Infecciosa (REIPI);Security Service of Andalusia

关键词: pandemic influenza;    pregnant women;    risk factors;    Spain;   

DOI  :  10.7883/yoken.67.163

学科分类：传染病学

来源: National Institute of Infectious Diseases

【 摘 要 】

References(55)Cited-By(1)The present study aimed to compare the main features of infection with pandemic influenza A virus in pregnant and nonpregnant women admitted to hospitals in Spain during the first waves of the 2009–2010 influenza pandemic. This was a prospective (November 2009 to June 2010), multicenter observational study. All cases were women of reproductive age who had not been vaccinated against seasonal or pandemic influenza A. Influenza infection was confirmed by reverse transcription-polymerase chain reaction (RT-PCR). The sociodemographic and clinical data of all cases were reviewed. A total of 219 inpatients, including 49 pregnant women and 170 nonpregnant women, were enrolled in the study upon admission to participating hospitals. The most substantially different symptoms between the groups were respiratory distress and unilobar consolidation, both of which were more frequent among nonpregnant women. Antibiotics and systemic corticosteroids were more frequently used in nonpregnant women; however, there were no differences in the rates of treatment with antivirals. Our findings indicated that the compared with nonpregnant women, pregnant women in this study did not have significantly different symptoms and were not at increased risk of complications from pandemic influenza virus infection.

【 授权许可】

Unknown