Journal of Veterinary Medical Science | |
CC Chemokine Receptor 4-Positive CD4+ Lymphocytes in Peripheral Blood Increases during Maturation in Healthy Beagles | |
Kenichi MASUDA2  Nobutaka YASUDA2  Sadatoshi MAEDA1  | |
[1] Department of Veterinary Internal Medicine, Faculty of Applied Biological Sciences, Gifu University;Animal Allergy Clinical Laboratories Inc. | |
关键词: canine; CCR4; lymphocyte; | |
DOI : 10.1292/jvms.70.989 | |
学科分类:兽医学 | |
来源: Japanese Society of Veterinary Science | |
【 摘 要 】
References(18)Cited-By(2)In this study, percentages of CCR4+ cells in peripheral CD4+ T-lymphocytes were examined with flow cytometry in 46 healthy beagles between 3 months and 7 years of age. The percentage of CCR4+ cells varied from 9.9% to 33.5%. The mean percentage was significantly lower in the group with ages of less than 1 year than those with ages equal to or more than 1 year (p<0.05), suggesting that maturation might increase the CCR4+ T-lymphocyte subset. No influence of aging on the percentages was detected among the groups with ages equal to or more than 1 year. The findings are useful for establishing a reference value for the percentage of peripheral CCR4+CD4+ lymphocytes in dogs.
【 授权许可】
Unknown
【 预 览 】
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RO201911300136612ZK.pdf | 151KB | download |