Comparison between the Comet Assay and Fast Micromethod® for Measuring DNA Damage in HeLa Cells

Croatica Chemica Acta

Bihari, Nevenka¹  Zahn, Rudolf K.³  Waldmann, Petra³  Jakšić, Željko¹  Batel, Renato¹  Müller, Werner E. G.² 

[1] Centre for Marine Research, Ruđer Bošković Institute, G. Paliaga 5, HR-52210 Rovinj, Croatia;Institute for Physiological Chemistry, Johannes Gutenberg University, Duesbergweg 6, D-55099 Mainz, Germany;AMMUG, Commission: Molecular Biology, Academy of Science and Literature, Obere Zahlbacher Straße 63, D-55101 Mainz, Germany

关键词: Fast Micromethod®;    Comet assay;    gamma rays;    UV-C light;    4-nitroquinoline-IV-oxide;    HeLa cells;    DNA damage;    environmental monitoring;   

DOI  :  

学科分类：化学（综合）

来源: Croatica Chemica Acta

【 摘 要 】

The sensitivity and precision of the single cell gel electrophoresis (Comet) assay and Fast Micromethod® for DNA damage determinations in human HeLa cell line were compared. The first assay allows analysis of DNA breaks in individual...

【 授权许可】

Unknown