In Addition to the High-Density Lipoprotein Fraction, Apolipoprotein C-III is Detected in Chylomicrons and the Very Low-Density Lipoprotein Fraction from Serum of Normolipidemic Cows

Journal of Veterinary Medical Science

Norio KATOH¹ 

[1] Hokkaido Research Station, National Institute of Animal Health

关键词: apolipoprotein C-III;    bovine;    chylomicron;    high-density lipoprotein;    very low-density lipoprotein;   

DOI  :  10.1292/jvms.63.95

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(13)Cited-By(5)Apolipoprotein (apo) C-III is a low-molecular-mass protein that is involved in the regulation of the triglyceride metabolism. Except for the hyperlipidemic calf, cattle apoC-III is mainly detected in the high-density lipoprotein (HDL) fraction, and the distribution in chylomicrons (CM) and the very low-density lipoprotein (VLDL) fraction has not yet been clarified. The purpose of the present study was to detect apoC-III in concentrated CM and VLDL fractions to examine whether apoC-III is distributed in the two fractions even in normolipidemic cattle. ApoC-III could be detected by immunoblot analysis in both concentrated cow CM and VLDL fractions, but not in the corresponding calf fractions. These results suggest that apoC-III is distributed in the CM and VLDL fractions, at least in cows, although the concentrations in these fractions are considerably lower than in the HDL fraction.

【 授权许可】

Unknown