Protective efficacy of stockpiled vaccine against H5N8 highly pathogenicavian influenza virus isolated from a chicken in Kumamoto prefecture, Japan, in2014

Journal of Veterinary Medical Science

Hiroshi KIDA¹  Koichiro GAMOH²  Yoshihiro SAKODA¹  Masatoshi OKAMATSU¹  Shoko SUZUKI²  Mari NAKAMIZO² 

[1] Laboratory of Microbiology, Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo 060�?0818, Japan;National Veterinary Assay Laboratory, Ministry of Agriculture, Forestry and Fisheries, 1�?15�?1 Tokura, Kokubunji, Tokyo 185�?8511, Japan

关键词: disease control;    efficacy;    highly pathogenic avian influenza;    low pathogenic avian influenza;    vaccine;   

DOI  :  10.1292/jvms.15-0324

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(16)H5 highly pathogenic avian influenza (HPAI) viruses have spread worldwide, andantigenic variants of different clades have been selected. In this study, the nationalstockpiled vaccine prepared from A/duck/Hokkaido/Vac-1/2004 (H5N1) strain was evaluatedfor the protective efficacy against H5N8 HPAI virus isolated in Kumamoto prefecture,Japan, in April 2014. In the challenge test, all of the vaccinated chickens survivedwithout showing any clinical signs and reduced virus shedding. It was concluded that thepresent stockpiled vaccine was effective against the H5N8 HPAI virus.

【 授权许可】

Unknown