期刊论文详细信息
Journal of Veterinary Medical Science
Limited Susceptibility of Pigeons Experimentally Inoculated with H5N1 Highly Pathogenic Avian Influenza Viruses
Masaji MASE1  Manabu YAMADA1  Yu YAMAMOTO1  Kikuyasu NAKAMURA1 
[1] National Institute of Animal Health
关键词: H5N1 subtype;    highly pathogenic avian influenza;    pigeons;   
DOI  :  10.1292/jvms.11-0312
学科分类:兽医学
来源: Japanese Society of Veterinary Science
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【 摘 要 】

References(28)Cited-By(8)An experimental infection study was performed using pigeons reared for racing or meat production in Japan and clade 2.2 and 2.3.2 isolates of H5N1 highly pathogenic avian influenza virus to evaluate the possible role of pigeons in virus transmission to poultry. In experiment 1, when 20 pigeons were intranasally inoculated with high or low viral doses, no inoculated pigeon exhibited clinical signs for 14 days. Drinking water and almost all swab samples were negative for virus isolation. Virus isolation was positive in 3 oral swab samples from 2 pigeons from day 2 through 4 postinoculation, but viral titers of positive samples were extremely low. Immunohistochemical analysis for virus detection was negative in all tissue samples. Along with seroconversion in a limited number of pigeons postinoculation, these results suggest that pigeons have limited susceptibility to the virus used for experimental infection. In experiment 2, when uninoculated chickens were housed with virus-inoculated pigeons, all pigeons and contact chickens survived for 14 days without exhibiting any clinical signs. According to serological analysis, the chickens did not exhibit seroconversion after close contact with inoculated pigeons. Our data suggest that the risk posed by pigeons with respect to the transmission of the H5N1 highly pathogenic avian influenza virus to poultry would be less than that for other susceptible avian species.

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