Lymphangiosarcoma with systemic metastases in a Japanese domesticcat

Journal of Veterinary Medical Science

Atigan THONGTHARB²  James K. CHAMBERS²  Kazuyuki UCHIDA²  Hiroyuki NAKAYAMA²  Ryohei NISHIMURA³  Ken-ichi WATANABE²  Manabu MOCHIZUKI⁴  Ayaka TAKAHASHI¹ 

[1] Veterinary Medical Center, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1�?1�?1 Yayoi, Bunkyo-ku, Tokyo 113�?8657, Japan;Department of Veterinary Pathology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1�?1�?1 Yayoi, Bunkyo-ku, Tokyo 113�?8657, Japan;Department of Veterinary Surgery, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1�?1�?1 Yayoi, Bunkyo-ku, Tokyo 113�?8657, Japan;Department of Veterinary Emergency Medicine, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1�?1�?1 Yayoi, Bunkyo-ku, Tokyo 113�?8657, Japan

关键词: feline;    lymphangiosarcoma;    metastases;   

DOI  :  10.1292/jvms.14-0502

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

References(25)A 4-year-2-month-old female Japanese domestic cat was diagnosed with lymphangiosarcomathrough tissue biopsy of an amputated leg. Two months later, the cat was euthanized, andpostmortem findings revealed edema, and bruising at the caudal region of the trunk,pulmonary hemorrhage, pulmonary nodules and mediastinal lymphadenopathy. Microscopically,neoplastic tissues were observed in the dermis and subcutis of the trunk, lung,mediastinal lymph nodes, diaphragm, omentum and mesentery. The tumor cells were spindle topolygonal-shaped with nuclear pleomorphism aligning along pre-existing collagen bundlesand forming irregular vascular channels in which the erythrocytes were rarely observed.These cells were immunopositive for vimentin, von Willebrand factor and CD31. Based on thehistopathological and immunohistochemical features, the neoplasia was diagnosed aslymphangiosarcoma with systemic metastases.

【 授权许可】

Unknown