Association of serum copper levels and glycemic control in patients with type 2 diabetes

Endocrine Journal

Naoto Katakami¹  Yoshimitsu Yamasaki¹  Ayako Harada¹  Munehide Matsuhisa²  Toyoko Naka¹  Hideaki Kaneto¹  Iichiro Shimomura¹  Taka-aki Matsuoka¹ 

[1] Department of Metabolic Medicine, Osaka University Graduate School of Medicine, Osaka, Japan;Diabetes Therapeutics and Research Center, Tokushima University, Tokushima, Japan

关键词: Copper;    Type 2 diabetes;    Hemoglobin A1c (HbA1c);   

DOI  :  10.1507/endocrj.EJ12-0342

学科分类：内分泌与代谢学

来源: Japan Endocrine Society

【 摘 要 】

References(15)Cited-By(10)It has been suggested that copper ion is involved in the pathogenesis of various diseases.The aim of this study is to examine the association of serum copper levels and glycemic control in patients with type 2 diabetes.We recruited a total of 132 patients with type 2 diabetes, and measured their serum copper levels by atomic absorption spectrometry.Serum copper levels were positively correlated with HbA1c levels (r=0.176, p=0 .044).In addition, after 3-month glycemic control, we evaluated whether the improvement of glycemic control influenced serum copper levels.As hemoglobin A1c (HbA1c) levels were decreased (from 8.7% to 6.8%, pp=0.069).In conclusion, it is likely that serum copper levels are associated with glycemic control in patients with type 2 diabetes.

【 授权许可】

Unknown