Efficacy of oral vaccine against bacterial coldwater disease in ayu Plecoglossus altivelis

Diseases of Aquatic Organisms

Nobuyasu Nakano¹  Masaya Okabe¹  Motoki Kondo¹  Kenji Kawai¹  Syun-ichirou Oshima¹ 

关键词: Oral vaccine;    Immunization;    Ayu;    Flavobacterium psychrophilum;    Bacterial coldwater disease;    BCWD;   

DOI  :  10.3354/dao055261

学科分类：生物科学（综合）

来源: Inter-Research

【 摘 要 】

ABSTRACT: The development of a practical vaccination method against bacterial coldwater disease (BCWD) in ayu Plecoglossus altivelis and the efficacy of oral administration of formalin-killed cells (FKCs) of Flavobacterium psychrophilum wasinvestigated. The FKC was administrated at a dose of 0.1-0.2 g kg^-1 body weight to juvenile ayu (0.5 g body weight) every day for 2 wk or on 5 days over 2 wk. Experimental immersion challenge at 3 and 7 wk after vaccination showed significantlyhigher survival rates than the controls. The results show the effectiveness of oral vaccination against BCWD in ayu.

【 授权许可】

Unknown