Plant–necrotroph co-transcriptome networks illuminate a metabolic battlefield

eLife

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[1] Department of Ecology and Evolution Biology, University of Colorado, Boulder, United States;Department of Plant Pathology, Kansas State University, Manhattan, United States;Department of Plant Pathology, Kansas State University, Manhattan, United States;Department of Plant Sciences, University of California, Davis, Davis, United States;Department of Plant Sciences, University of California, Davis, Davis, United States;Department of Plant Sciences, University of California, Davis, Davis, United States;DynaMo Center of Excellence, University of Copenhagen, Frederiksberg, Denmark;

关键词: host-pathogen Interaction;    co-transcriptome;    gene co-expression network;    pathosystem;    Arabidopsis;    Botrytis cinerea;    A. thaliana;   

DOI  :  10.7554/eLife.44279

来源: publisher

【 摘 要 】

10.7554/eLife.44279.001A central goal of studying host-pathogen interaction is to understand how host and pathogen manipulate each other to promote their own fitness in a pathosystem. Co-transcriptomic approaches can simultaneously analyze dual transcriptomes during infection and provide a systematic map of the cross-kingdom communication between two species. Here we used the Arabidopsis-B. cinerea pathosystem to test how plant host and fungal pathogen interact at the transcriptomic level. We assessed the impact of genetic diversity in pathogen and host by utilization of a collection of 96 isolates infection on Arabidopsis wild-type and two mutants with jasmonate or salicylic acid compromised immunities. We identified ten B. cinereagene co-expression networks (GCNs) that encode known or novel virulence mechanisms. Construction of a dual interaction network by combining four host- and ten pathogen-GCNs revealed potential connections between the fungal and plant GCNs. These co-transcriptome data shed lights on the potential mechanisms underlying host-pathogen interaction.

【 授权许可】

CC BY