Assessing ventilatory instability using the response to spontaneous sighs during sleep in preterm infants

Sleep

Carroll, John L^6¹  Khoo, Michael C^4²  Sands, Scott A^3³  Landry, Shane A^1,2⁴  Kemp, James S^5⁵  Terrill, Philip I^7⁶  Nava-Guerra, Leonardo^4⁷  Edwards, Bradley A^1,2,3⁸ 

[1] Department of Biomedical Engineering, University of Southern California, Los Angeles, CA^4;Division of Allergy, Immunology and Pulmonary Medicine, Department of Pediatrics, Washington University School of Medicine, St. Louis, MO^5;Division of Pediatric Pulmonary and Sleep Medicine, Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AR^6;Division of Pulmonary Medicine, Department of Pediatrics, Cincinnati Children Hospital Medical Center, Cincinnati, OH^8;Division of Sleep and Circadian Disorders, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA^3;School of Information Technology and Electrical Engineering, University of Queensland, Brisbane, Australia^7;School of Psychological Sciences and Monash Institute of Cognitive and Clinical Neurosciences, Monash University, Melbourne, Australia^2;Sleep and Circadian Medicine Laboratory, Department of Physiology, Monash University, Melbourne, Australia^1

关键词: breathing control;    breathing physiology;    pediatrics - breathing control;    pediatrics - infants;    periodic breathing;    loop gain;    neonates;   

DOI  :  10.1093/sleep/zsy161

学科分类：生理学

来源: American Academy of Sleep Medicine

【 摘 要 】

Study ObjectivesPeriodic breathing (PB) is common in newborns and is an obvious manifestation of ventilatory control instability. However, many infants without PB may still have important underlying ventilatory control instabilities that go unnoticed using standard clinical monitoring. Methods to detect infants with “subclinical” ventilatory control instability are therefore required. The current study aimed to assess the degree of ventilatory control instability using simple bedside recordings in preterm infants.

【 授权许可】

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