A Multi-Well Thin-Si LAPS and All-in-One Readout System for Ion Activity Monitor of Epithelium Cells

Proceedings

Lo, Chih-Hong¹  Liu, Hui-Ling²  Lin, Po-Yen³  Wu, Tsung-Ru⁴  Chin, Wei-Chun⁵  Chen, Yu-Ping⁶  Lai, Hsin-Chih⁷  Lin, Yu-Jing⁸  Hwang, Tsann-Long⁹ 

[1] Author to whom correspondence should be addressed.;Bioengineering Department, University of California, Merced, CA 95343, USA;Department of Electronic Engineering, Chang Gung University, Taoyuan 333, Taiwan;Department of General Surgery, Chang Gung Memorial Hospital at Linkou, Taoyuan 333, Taiwan;Department of Materials Engineering, Ming Chi University of Technology, New Taipei City 24301, Taiwan;Department of Medical Biotechnology and Laboratory Science, Chang Gung University, Taoyuan 333, Taiwan;Department of Nephrology, Chang Gung Memorial Hospital at Linkou, Taoyuan 333, Taiwan;Institute of Electro-Optical Engineering, Chang Gung University, Taoyuan 333, Taiwan;Presented at the Eurosensors 2018 Conference, Graz, Austria, 9–12 September 2018

关键词: 2D image;    cell culture;    LAPS;   

DOI  :  10.3390/proceedings2131020

学科分类：社会科学、人文和艺术（综合）

来源: mdpi

【 摘 要 】

To measure the ion activities of cells, an easy-access and fully-integrated system is necessary in culture room with high cleanness and easy maintenance. A new sensor structure integrated with readout system based on light-addressable potentiometric sensor (LAPS) to quantitatively monitor real-time cell activity with the advantages of label free and 2D image ability is proposed. The difference of cell number and acidification could be easily observed by 2D images by means of this proposed methodology.

【 授权许可】

CC BY