Melatonin Does Not Alter Cell Proliferation in Metastatic Breast Cancer Cells

Proceedings

Erin, Nuray¹  Dilmac, Sayra²  Tanriover, Gamze³ 

[1] Author to whom correspondence should be addressed.;Department of Medical Pharmacology, Medical Faculty, Akdeniz University, 07070 Antalya, Turkey;Dept. Histology and Embryology, Akdeniz University, 07070 Antalya, Turkey

关键词: breast cancer;    melatonin;    doxorubicin;    WST;   

DOI  :  10.3390/proceedings2251567

学科分类：社会科学、人文和艺术（综合）

来源: mdpi

【 摘 要 】

Breast cancer treatments continue to be investigated with supported by new treatment methods. Melatonin is a hormone that can be effective in the treatment of breast cancer due to its anti-oxidant effect. Melatonin had previously shown to inhibit proliferation of cancer cells. In this study, we aimed to determine the effect of melatonin on the proliferation of metastatic breast cancer cells in comparison to doxorubicin, a well-known chemotherapeutic agent. Doxorubicin inhibited proliferation of metastatic breast cancer cells while melatonin has no effect. We are currently examining the effects of melatonin and doxorubicin combination therapy on metastatic breast cancer cells.

【 授权许可】

CC BY