Nitrate reductase assay using sodium nitrate for rapid detection of multidrug resistant tuberculosis

Revista de microbiologia

Groll, Andrea Von¹  Macedo, Maíra Bidart² 

[1] Institute of Tropical Medicine, Antwerp, Belgium;Universidade Federal do Rio Grande, Rio Grande, Brasil

关键词: nitrate reductase assay;    tuberculosis;    multidrug resistant;    sodium nitrate.;   

DOI  :  10.1590/S1517-83822012000300019

学科分类：农业科学（综合）

来源: Sociedade Brasileira de Microbiologia / Brazilian Society for Microbiology

【 摘 要 】

We validated the nitrate reductase assay (NRA) for the detection of multidrug-resistant Mycobacterium tuberculosis (MDR-TB) using sodium nitrate (NaNO3) in replacement of potassium nitrate (KNO3) as nitrate source. NaNO3 is cheaper than KNO3 and has no restriction on use which facilitates the implementation of NRA to detect MDR-TB.

【 授权许可】

CC BY-NC