Mapping of the continuous epitopes displayed on the Clostridium perfringens type D epsilon-toxin

Revista de microbiologia

Alves, Guilherme Guerra¹  Machado-de-Ávila, Ricardo Andrez² 

[1] Universidade Federal de Minas Gerais, Belo Horizonte, Brazil;Universidade do Extremo Sul Catarinense, Criciúma, Brazil

关键词: Epsilon;    Toxin;    Enterotoxemia;    Epitope;    Mapping.;   

DOI  :  10.1016/j.bjm.2016.10.023

学科分类：农业科学（综合）

来源: Sociedade Brasileira de Microbiologia / Brazilian Society for Microbiology

【 摘 要 】

The epsilon toxin, produced by Clostridium perfringens, is responsible for enterotoxemia in ruminants and is a potential bioterrorism agent. In the present study, 15 regions of the toxin were recognized by antibodies present in the serum, with different immunodominance scales, and may be antigen determinants that can be used to formulate subunit vaccines.

【 授权许可】

CC BY-NC