Consensus Guidelines on the Use of Superficial Radiation Therapy for Treating Nonmelanoma Skin Cancers and Keloids

The Journal of Clinical and Aesthetic Dermatology

Jr.¹  David Goldberg²  Michael Gold³  Arm⁴  Brian Berman⁵  B. Cognetta⁶  Mark S. Nestor⁷ 

[1] Dr. Cockerell is with Cockerell Dermatopathology in Dallas, Texas.;Dr. Cognetta is with Dermatology Associates of Tallahassee in Tallahassee, Florida.;Dr. Glick is with the Glick Skin Institute in Margate, Florida.;Dr. Gold is with Gold Skin Care Center, the Tennessee Clinical Research Center, Vanderbilt University School of Nursing, and Meharry Medical College School of Medicine in Nashville, Tennessee.;Dr. Goldberg is with Skin Laser Surgery Specialists of NY/NJ, Icahn School of Medicine at Mount Sinai, and Fordham Law School in New York, New York.;Dr. Roth is with Dermatology and Dermatological Surgery in Boynton Beach, Florida.;Drs. Nestor and Berman are with the Center for Clinical and Cosmetic Research in A ventura, Florida and the Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine in Miami, Florida.

关键词: Superficial radiation therapy;    nonmelanoma skin cancer;    literature review;    consensus guidelines;   

DOI  :  

学科分类：医学（综合）

来源: Matrix Medical Communications, LLC

【 摘 要 】

Background: The use of superficial radiation therapy (SRT) has experienced a renaissance for treating nonmelanoma skin cancers (NMSCs) and recurrent keloids; however, published treatment guidelines are lacking. Objective: The objective of this work was to provide consensus guidelines on the use of SRT for treating NMSC and recurrent keloids based on a review of the literature and expert opinion. Methods and Materials: A search of the medical literature was performed to obtain published information on the use of SRT for review. A group of qualified dermatologists convened to discuss their views on the use of SRT for the treatment of NMSCs and recurrent keloids. The various guidelines were considered to have consensus based on a supermajority two-thirds vote. The final consensus guidelines are thus based on the medical literature, when available, and expert opinions. Results: Agreement on consensus guidelines was reached for numerous aspects of SRT use, including appropriate tumor types for SRT; anatomical areas suitable for SRT; energy, fractions, and scheduling recommendations for SRT; use of SRT in the presence of comorbidities; safety factors; and treatment recommendations for recurrent keloids, based the literature and on both the opinions of the expert group and a survey of experienced users. Conclusion: Consensus was reached that SRT is a safe and effective treatment for basal cell and squamous cell carcinomas and should be considered as the first-line form of radiation treatment. Postsurgical treatment of keloid excision suture lines with SRT significantly reduces keloid recurrence rates.

【 授权许可】

Unknown