Revista de microbiologia | |
Alternariol 9-methyl ether from the endophytic fungus Alternaria sp. Samif01 and its bioactivities | |
Lou, Jingfeng1  Yu, Ruiting2  | |
[1] China Agricultural University, Beijing, China;Chinese Academy of Agricultural Sciences, Beijing, China | |
关键词: Salvia miltiorrhiza Bunge; Endophytic fungus; Alternaria sp.; Alternariol 9-methyl ether; Bioactivity.; | |
DOI : 10.1016/j.bjm.2015.11.004 | |
学科分类:农业科学(综合) | |
来源: Sociedade Brasileira de Microbiologia / Brazilian Society for Microbiology | |
【 摘 要 】
One bioactive compound, identified as alternariol 9-methyl ether, was isolated from the crude extract of the endophytic fungus Alternaria sp. Samif01 residing in the roots of Salvia miltiorrhiza Bunge. Alternariol 9-methyl ether was active against bacteria with minimum inhibitory concentration values ranging from 25 to 75 µg/mL and median inhibitory concentration (IC50) values ranging from 16.00 to 38.27 µg/mL. The IC50 value of alternariol 9-methyl ether against spore germination of Magnaporthe oryzae was 87.18 µg/mL. Alternariol 9-methyl ether also showed antinematodal activity against Bursaphelenchus xylophilus and Caenorhabditis elegans with IC50 values of 98.17 µg/mL and 74.62 µg/mL, respectively. This work is the first report on alternariol 9-methyl ether and its biological activities from the endophytic fungus Alternaria sp. Samif01 derived from S. miltiorrhiza Bunge. The results indicate the potential of Alternaria sp. Samif01 as a source of alternariol 9-methyl ether and also support that alternariol 9-methyl ether is a natural compound with high potential bioactivity against microorganisms.
【 授权许可】
CC BY-NC
【 预 览 】
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