Intense Circuit Resistance Training along with Zataria multiflora Supplementation Reduced Plasma Retinol Binding Protein-4 and Tumor Necrosis Factor-α in Postmenopausal Females

Jundishapur Journal of Natural Pharmaceutical Products

Seyed Morteza Tayebi¹  Peiman Hasannezhad²  Ayoub Saeidi³ 

[1] Core Research of Health Physiology and Physical Activity, Department of Exercise Physiology, Faculty of Sport Science, Allameh Tabataba’i University, Tehran, IR Iran;Department of Physical Education and Sport Science, Rasht branch, Islamic Azad University, Rasht, IR Iran;Exercise Biochemistry Division, Faculty of Sport Science, University of Mazandaran, Babolsar, IR Iran

关键词: Intense Circuit Resistance Training along with <;    i>;    Zataria multiflora<;    /i>;    Supplementation Reduced Plasma Retinol Binding Protein-4 and Tumor Necrosis Factor-α in Postmenopausal Females;    Circuit Resistance Training;    Retinol Binding Protein-4;    Tumor Necrosis Factor-α;    Postmenopausal Females;    Zataria multiflora Supplementation;    articles;    55317;   

DOI  :  10.17795/jjnpp.38578

学科分类：药理学

来源: Jundishapur Journal of Natural Pharmaceutical Products

【 摘 要 】

It is observed that the levels of retinol binding protein-4 (RBP-4) and cytokine tumor necrosis factor-α (TNF-α) in people with obesity, diabetes and low physical activity, such as postmenopausal females, are more than those of the healthy individuals. The current study aimed to investigate the effect of eight weeks of circuit resistance training (CRT) and Zataria multiflora supplementation (ZMSuppl) on RBP-4 and TNF-α in postmenopausal females.Forty-eight untrained postmenopausal females participated in the study and were divided into four groups (n = 12) of control (Con), CRT, ZMSuppl and CRT along with ZMSuppl (CRT + ZMSuppl). CRT program included 12 stations (30 seconds for each station, 85% one repetition maximum) for eight weeks (three sessions/week). 500 mg of ZMSuppl was consumed daily after breakfast in ZMSuppl and CRT + ZMSuppl groups. Blood samples were taken 48 hours before the first session and 48 hour after the last session of training to measure plasma RBP-4 and TNF-α.A significant reduction was observed in plasma TNF-α in the CRT + ZMSuppl group in comparison with Con (P < 0.05). In addition, a significant reduction was observed in plasma RBP-4 in both CRT and CRT + ZMSuppl groups in comparison with Con (P < 0.01) and ZMSuppl (P < 0.01).The current study showed that intense CRT causes significant reduction only in plasma RBP-4; but this reduction was higher in RBP-4 and also in TNF-α, when ZMSuppl was added to CRT. Therefore, it may be an effective method to reduce disorders and abnormalities related to inflammatory factors resulting from menopause.

【 授权许可】

CC BY-NC