Therapeutic effects of oral clomiphene citrate in 2 dogs with low plasma testosterone levels and poor semen quality

The Journal of Veterinary Medical Science

Masanori KOBAYASHI¹ 

[1] Laboratory of Reproduction, Faculty of Veterinary Medicine, Nippon Veterinary and Life Science University, 1-7-1 Kyonan-cho, Musashino-shi, Tokyo 180-8602, Japan

关键词: clomiphene citrate;    oral administration;    semen quality;    spermatogenic dysfunction;    testosterone;   

DOI  :  10.1292/jvms.18-0108

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

Two dogs with low plasma testosterone (T) levels and poor semen quality were administered one tablet of 12.5 mg clomiphene citrate orally per day at 2-day intervals for 4 weeks. Plasma T levels, total sperm count, and sperm motility in both dogs temporarily increased between 3 and 6 weeks after the start of treatment. These results indicate that poor semen quality in dogs with low plasma T level can be improved by oral administration of clomiphene citrate.

【 授权许可】

Unknown