HColonDB: A Database for Human Colon Cancer Research

Journal of computational biology: A journal of computational molecular cell biology

YichenXu^1¹  XiaodanMao^1² 

[1] Address correspondence to: Dr. Zhenran Jiang, Department of Computer Science and Technology, East China Normal University, North Zhongshan Road Campus, 3663 N. Zhongshan Rd., Shanghai 200062, China^2;Department of Computer Science and Technology, East China Normal University, Shanghai, China^1

关键词: database;    human colon cancer;    information integration;   

DOI  :  10.1089/cmb.2018.0193

学科分类：生物科学（综合）

来源: Mary Ann Liebert, Inc. Publishers

【 摘 要 】

HColonDB (Human Colon cancer Database) is an important database which integrates genes, pathways, networks, drugs, and other information related to colon cancer. The purpose of the database is to provide a platform for the systematic research of colon cancer. The relationships between genes and pathways, genes and networks, and networks and pathways are obtained from the database KEGG. Furthermore, the information of the drugs used to treat colon cancer is available in HColonDB, which is collected and organized from DrugBank and PubChem database. In brief, we have summarized 81 genes, 112 pathways, 108 networks, and 15 drugs associated with colon cancer. The current version of HColonDB contains 322 associations between genes and pathways, 242 associations between genes and networks, and 68 associations between networks and pathways. In addition, HColonDB provides a friendly interface for users to browse and search. We hope that the database can make it more convenient for researchers to get the data they need and help in the treatment of colon cancer.

【 授权许可】

Unknown