Diarrheagenic Escherichia coli

Revista de microbiologia

Elias, Waldir P.¹  Gomes, Tânia A.T.²  Scaletsky, Isabel C.A.³ 

[1] Instituto Butantan, São Paulo, Brazil;Universidade Federal de São Paulo, São Paulo, Brazil;Universidade de São Paulo, São Paulo, Brazil

关键词: Escherichia coli;    Diarrhea;    Pathogenic mechanisms;    Virulence factor;    Epidemiology.;   

DOI  :  10.1016/j.bjm.2016.10.015

学科分类：农业科学（综合）

来源: Sociedade Brasileira de Microbiologia / Brazilian Society for Microbiology

【 摘 要 】

Most Escherichia coli strains live harmlessly in the intestines and rarely cause disease in healthy individuals. Nonetheless, a number of pathogenic strains can cause diarrhea or extraintestinal diseases both in healthy and immunocompromised individuals. Diarrheal illnesses are a severe public health problem and a major cause of morbidity and mortality in infants and young children, especially in developing countries. E. coli strains that cause diarrhea have evolved by acquiring, through horizontal gene transfer, a particular set of characteristics that have successfully persisted in the host. According to the group of virulence determinants acquired, specific combinations were formed determining the currently known E. coli pathotypes, which are collectively known as diarrheagenic E. coli. In this review, we have gathered information on current definitions, serotypes, lineages, virulence mechanisms, epidemiology, and diagnosis of the major diarrheagenic E. coli pathotypes.

【 授权许可】

CC BY-NC