Biological properties of Elaeagnus rhamnoides (L.) A. Nelson twig and leaf extracts

BMC Complementary and Alternative Medicine

  ^{1    1    1    1    2    3    3} 

[1] 0000 0000 9730 2769, grid.10789.37, Department of General Biochemistry, Faculty of Biology and Environmental Protection, University of Łódź, Pomorska 141/3, 90-236, Łódź, Poland;0000 0001 2149 6795, grid.412607.6, Department of Neurology and Neurosurgery, Faculty of Medical Sciences, University of Warmia and Mazury, Warszawska 30, 10-082, Olsztyn, Poland;0000 0004 0369 196X, grid.418972.1, Department of Biochemistry, Institute of Soil Science and Plant Cultivation, State Research Institute, Czartoryskich 8, 24-100, Puławy, Poland;

关键词: Oxidative stress;    Elaeagnus rhamnoides;    Twig;    Leaf;    Berry;    Phenolic compounds;    Hemostasis;   

DOI  :  10.1186/s12906-019-2564-y

来源: publisher

【 摘 要 】

BackgroundSea buckthorn (Elaeagnus rhamnoides (L.) A. Nelson, SBT) is a valuable plant because of its medical and therapeutic potential. Different bioactive compounds in SBT berries are of special interest to various researchers. However, not only sea buckthorn berries, but also leaves of this plant (both fresh and dried) contain a lot of nutrients and bioactive compounds, including phenolic compounds. The present study was carried out in order to investigate antioxidant and anticoagulant properties of sea buckthorn twig and leaf extracts (0.5–50 μg/mL) by using various in vitro models. Moreover, the aim of present experiments was to compare the biological activity of SBT leaf extract and SBT twig extract with selected berry extracts (a rich source of phenolic compounds): SBT berry extract (flavonoids being the dominant components), a commercial extract from the berries of Aronia melanocarpa (Aronox®), and a grape seed extract.MethodsWe determined the effect of plant extracts on the oxidative stress using selected markers of this process, i.e. the level of carbonyl groups in proteins. Additionally, we analysed the potential mechanism of modulation of hemostatic properties of human plasma (using selected coagulation times).ResultsSBT twig and leaf extracts were observed to exhibit an antioxidant activity against two strong biological oxidants: hydrogen peroxide (H2O2) and H2O2/Fe (the donor of hydroxyl radicals), which induced human plasma lipid peroxidation and protein carbonylation. Both extracts also showed anticoagulant properties.ConclusionsOur present results have demonstrated that extracts from different parts of SBT, especially berries and twigs, in comparison to well-known berries (aronia and grape), may also be viewed as a good source of active substances – antioxidants for pharmacological or cosmetic applications. Moreover, it is very important from an economic point of view to know that there is a possibility of obtaining phenolic compounds not only from the berries or leaves, but also from twigs, which constitute a production waste.

【 授权许可】

CC BY