Overexpression of Aldose Reductase Render Mouse Hepatocytes More Sensitive to Acetaminophen Induced Oxidative Stress and Cell Death

Indian journal of clinical biochemistry: IJCB

Munzir M. E. Ahmed¹ 

关键词: Aldose reductase;    Acetaminophen;    APAP;    Oxidative stress;    ROS;    AML-12;   

DOI  :  10.1007/s12291-015-0517-x

学科分类：过敏症与临床免疫学

来源: Springer

【 摘 要 】

Acetaminophen (APAP) a commonly used drug for decrease the fever and pain but is capable to induced hepatotoxicity at over dose. This study was carried out to investigate the effect of APAP on the expression of anti-apoptotic and antioxidative defense ...

【 授权许可】

CC BY