Revista Chilena de Enfermedades Respiratorias | |
Tratamiento del asma severo con Omalizumab: experiencia pediátrica en Chile y revisión de la literatura | |
CRUZ B, CAROLINA1  CAMPUSANO T, LUIS1  HERRERA G, ANA MARÃA2  PERILLÃN T, JOSÃ ANTONIO3  LEZANA S, VIVIANA4  ÃLVAREZ G, CECILIA4  MARINOVIC M, MARÃA ANGÃLICA5  NAVARRETE C, PAMELA6  HERNÃNDEZ C, JURY7  | |
[1] ClÃnica Alemana de Santiago, Santiago, Chile;ClÃnica Santa MarÃa, Chile;Complejo Asistencial Dr. VÃctor RÃos Ruiz, Los Ãngeles, Chile;Hospital San Juan de Dios, Chile;Universidad de Chile, Santiago, Chile;Universidad de ValparaÃso, ValparaÃso, Chile;Universidad de los Andes, Chile | |
关键词: Omalizumab; asthma; anti-asthmatic agents; antibodies; anti-idiotypic; child; quality of life.; | |
DOI : 10.4067/S0717-73482016000300004 | |
学科分类:社会科学、人文和艺术(综合) | |
来源: Sociedad Chilena de Enfermedades Respiratorias | |
【 摘 要 】
This paper presents clinical experience with Omalizumab treatment in 8 pediatric patients in Chile. All children presented difficult to control asthma despite receiving high intensity treatment, with low quality of life. All patients were studied in order to discard errors in asthma diagnosis and to evaluate asthma treatment adherence and inhalation technique. After evaluation, patients proven to have severe therapy resistant asthma were indicated treatment with Omalizumab. Significant clinical improvement was observed, with reduced asthma symptoms and number of exacerbations, as well as an improved quality of life. Omalizumab showed a good safety profile with mild and transient adverse reactions in 6 administrations of a total of 122.
【 授权许可】
CC BY
【 预 览 】
Files | Size | Format | View |
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RO201904280795238ZK.pdf | 314KB | download |