Plasma Levels of Glucose and Insulin in Patients with Brain Tumors

Current Health Sciences Journal

Oana Alexandru ; L. Ene ; Oana Stefana Purcaru ; Daniela Elise Tache ; Alisa Popescu ; Oana Maria Neamtu ; Ligia Gabriela Tataranu ; Ada Maria Georgescu ; Valerica Tudorica ; Cornelia Zaharia ; Anica Dricu

关键词: brain tumors;    relations;    glucose;    insulin;   

学科分类：医学（综合）

来源: Universitatea de Medicina si Farmacie din Craiova / University of Medicine and Pharmacy

【 摘 要 】

In the last years there were many authors that suggest the existence of an association between different components of metabolic syndrome and various cancers. Two important components of metabolic syndrome are hyperglycemia and hyperinsulinemia. Both of them had already been linked with the increased risk of pancreatic, breast, endometrial or prostate cancer. However the correlation of the level of the glucose and insulin with various types and grades of brain tumors remains unclear. In this article we have analysed the values of plasma glucose and insulin in 267 patients, consecutively diagnosed with various types of brain tumors. Our results showed no correlation between the glycemia and brain tumor types or grades. High plasma levels ofinsulin were found in brain metastasis and astrocytomas while the other types of brain tumors (meningiomas and glioblastomas) had lower levels of the peptide. The levels of insulin were also higher in brain metastasis and grade 3 brain tumors when compared with grade 1, grade 2 and grade 4 brain tumors.

【 授权许可】

Unknown