期刊论文详细信息
| Journal of Leukocyte Biology: An Official Publication of the Reticuloendothelial Society | |
| mTOR and metabolic regulation of conventional and regulatory T cells | |
| 关键词: metabolism; Tregs; T cell differentiation; lipid; glycolysis; | |
| DOI : 10.1189/jlb.2RI0814-408R | |
| 学科分类：生理学 | |
| 来源: Federation of American Societies for Experimental Biology | |
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【 摘 要 】
mTORsignalinglinksbioenergeticandbiosyntheticmetabolismtoimmuneresponses.mTORisactivatedbydiverseupstreamstimuli,includingimmunesignals,growthfactors,andnutrients.RecentstudieshighlightcrucialrolesofmTORsignalinginimmunefunctionsmediatedbyconventionalTcellsandTregs.Inthisreview,wediscusstheregulationofmTORsignalinginTcellsandthefunctionalimpactsofmTORandmetabolicpathwaysonTcell‐mediatedimmuneresponses,withaparticularfocusonthedifferentiationandfunctionofTregs...
【 授权许可】
CC BY
【 预 览 】
| Files | Size | Format | View |
|---|---|---|---|
| RO201904049707615ZK.pdf | 823KB |  download |
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