期刊论文详细信息
Journal of Leukocyte Biology: An Official Publication of the Reticuloendothelial Society | |
Th17 memory cells: live long and proliferate | |
关键词: autoimmunity; CD4 T cell; IL‐; 17; pathogen; | |
DOI : 10.1189/jlb.0313113 | |
学科分类:生理学 | |
来源: Federation of American Societies for Experimental Biology | |
【 摘 要 】
Thedevelopmentofimmunememoryisadouble‐edgedsword,helpingtomaintainhealthbypreventingrepeatedinfectionsbutalsodrivingchronicinflammationwhendysregulated.Th17cellsarenowwell‐knownasmajordriversofautoimmunediseasebutalsoplayrolesinprotectiveimmuneresponsesagainstpathogens.Thismini‐reviewwillfocusontherecentevidenceforlong‐lived,robustTh17memorycellpopulationsinmousemodelsandhumans,andtheirfunctionalrolesinmediatinghostprotectionandchronicdiseasestates...
【 授权许可】
CC BY
【 预 览 】
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