期刊论文详细信息
Cardiorenal medicine
A Common APOE Polymorphism Is an Independent Risk Factor for Reduced Glomerular Filtration Rate in the Spanish RENASTUR Cohort
Eliecer Coto ; Juan Gómez ; Beatriz Tavira ; Salvador Tranche ; Francisco Ortega ; María I. Rodríguez ; Emilio Sánchez ; Rafael Marín ; Ana I. Corao ; Jorge Arenas ; Victoria Alvarez
关键词: APOE polymorphisms;    Type 2 diabetes mellitus;    Glomerular filtration rate;    Renal function;   
DOI  :  10.1159/000351158
学科分类:心脏病和心血管学
来源: S Karger AG
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【 摘 要 】

Abstract Objective: APOE gene variants may contribute to the risk of chronic kidney disease. Our aim was to determine whether the common APOE-2/3/4 polymorphism is associated with a reduced estimated glomerular filtration rate (eGFR) in the RENASTUR population, a cohort of elderly individuals from the region Asturias (northern Spain). Methods: A total of 743 Spanish Caucasians aged 55.

【 授权许可】

CC BY   

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