Markers of subclinical atherosclerosis and cardiovascular risk in young adults horizontally infected with HIV-1 during infancy

Current Health Sciences Journal

FLORENTINA DUMITRESCU1¹ 

关键词: HIV;    young;    atherosclerosis;    cardiovascular risk;   

DOI  :  10.12865/CHSJ.39.02.03

学科分类：医学（综合）

来源: Universitatea de Medicina si Farmacie din Craiova / University of Medicine and Pharmacy

【 摘 要 】

Objectives to evaluate the markers of subclinical atherosclerosis and to identify a potential cardiovascular risk (CVR) profile in young adults horizontally infected with HIV-1 during infancy.Methods prospective randomized study, carried out between 01 January 2010 and 30 June 2010, on 56 HIV infected persons (PIH) parenterally infected with HIV-1 during 1988-1990, following antiretroviral treatment (ART), under surveillance of Craiova HIV/AIDS Regional Center, Romania. Variables followed personal history and clinical data, traditional and additional CVR factors, metabolic, immunological and virological parameters, inflammation markers (high-sensitivity C reactive proteine- hs-CRP), ultrasound data regarding carotid intima-media thickness (IMT). Twenty-six HIV-seronegative young adults were assigned as control group (CG) for metabolic parameters, hs-CRP and IMT. Results general characteristics of the group average age = 20.82 ± 1.1 years, equal gender distribution, 47 PIH (83.9.

【 授权许可】

Unknown