奥美拉唑所致245例不良反应文献分析

Zhongxiyi Jiehe Huli (Zhong-Yingwen Ban)

罗玉茹¹ 

关键词: 奥美拉唑;    药物不良反应;    消化系统;    血液系统;    神经系统;   

DOI  :  10.11997/nitcwm.201801012

学科分类：护理学

来源: Shanghai Jiao Tong University Press

【 摘 要 】

Abstract：Objective To analyze the studies on adverse drug reactions(ADR)induced by omeprazole and provide reference for clinical rational drug use. Methods 〓To set “omeprazole” and “adverse effect” as the key words, the literatures relevant to ADR induced by omeprazole in Embase and Pubmed during 1990―2016 were retrieved, and the patient's information were analyzed. Results 〓Totally 245 cases were retrieved, among which 137 cases were male(55.92%); occurs in 60 to 80(excluding 80)years of age(98 cases, 40%); route of administration was mainly oral administration(236 cases, 96.33%); ADR occurrence in two time periods, which in 2-10 d and >30 d; ADR involved organs and(or)system is extensive, mainly about the digestive system, blood system, nervous system, endocrine and reproductive system. Conclusion 〓More attention should be paid on the increasing adverse drug reactions caused by omeprazole.

【 授权许可】

CC BY-NC