Effectiveness of Platelet-rich Plasma Injection for Rotator Cuff Tendinopathy: A Prospective Open-label Study:

Global Advances in Health and Medicine

MichaelScarpone¹ 

关键词: Platelet rich plasma;    PRP;    rotator cuff tendinopathy;   

DOI  :  10.7453/gahmj.2012.054

学科分类：医学（综合）

来源: Sage Journals

【 摘 要 】

Objective:Assess platelet rich plasma (PRP) injection for rotator cuff tendinopathy (RCT).Design:Prospective open label study with 1-year follow-up.Methods:Participants recruited from an outpatient sports medicine clinic had clinically and magnetic resonance image (MRI)—demonstrated RCT refractory to physical therapy and corticosteroid injection. They received one ultrasound-guided injection of 3.0 mL of 1% xylocaine followed by 3.5 mL of PRP at the lesion and surrounding tendon. Primary outcome: 0—10 visual analog scale (VAS; baseline, 8, 12, and 52 weeks). Secondary outcomes: functional shoulder tests assessing rotator cuff strength and endurance (at baseline and 8 and 12 weeks), MRI severity (1—5 points [at baseline and 4 and 8 weeks]), and patient satisfaction (52 weeks).Results:Eighteen participants with 19 assessed shoulders reported VAS pain score improvement from 7.5 ± 0.3 points to 0.5 ± 0.3 points by week 12 and 0.4 ± 0.2 (P = .0001) points at week 52. Functional outcomes significantly improved;...

【 授权许可】

CC BY