CD34/CD133 enriched bone marrow progenitor cells promote neovascularization of tissue engineered constructs in vivo - ScienceDirect

Stem Cell Research

Marietta Herrmann¹ 

关键词: AAALAC;    Association for Assessment and Accreditation of Laboratory Animal Care international;    acLDL;    Acetylated low density lipoprotein;    BM;    Bone marrow;    CEPC;    Circulating EPC;    EC;    Endothelial cell;    EPC;    Endothelial progenitor cell;    EPCC;    Endothelial progenitor containing cell population;    FACS;    Fluorescence activated cell sorting;    HA;    Hydroxyapatite;    HUVEC;    Human umbilical vein endothelial cell;    MACS;    Magnetic associated cell sorting;    MNC;    Mononuclear cells;    PDGF;    Platelet derived growth factor;    PL;    Platelet lysate;    PRP;    Platelet rich plasma;    PU;    Polyurethane;    RANTES;    Regulated on activation, normal T cell expressed and secreted;    RT;    Room temperature;    SEM;    Standard error of the mean;    VEGF;    Vascular endothelial growth factor;   

DOI  :  10.1016/j.scr.2014.10.005

学科分类：生物科学（综合）

来源: Elsevier

【 摘 要 】

Vascularization is critical for 3D tissue engineered constructs. In large size implants the ingrowth of vessels often fails. The purpose of this study was to identify an easily accessible, clinically relevant cell source able to promote neovascularization in engineered implants in vivo and to establish an autologous culture method for these cells.

【 授权许可】

Unknown