Granular Cell Tumor Imaging Using Optical Coherence Tomography:

Biomedical Engineering and Computational Biology

DavidTes¹ 

关键词: Optical coherence tomography;    tumor border detection;    granular cell tumor;    image processing;    image analysis;    attenuation coefficient;   

DOI  :  10.1177/1179597218790250

学科分类：工程和技术（综合）

来源: Sage Journals

【 摘 要 】

Background:Granular cell tumor (GCT) is a relatively uncommon tumor that may affect the skin. The tumor can develop anywhere on the body, although it is predominately seen in oral cavities and in the head and neck regions. Here, we present the results of optical coherence tomography (OCT) imaging of a large GCT located on the abdomen of a patient. We also present an analytical method to differentiate between healthy tissue and GCT tissues.Materials and methods:A multibeam, Fourier domain, swept source OCT was used for imaging. The OCT had a central wavelength of 1305 ± 15 nm and lateral and axial resolutions of 7.5 and 10 µm, respectively. Qualitative and quantitative analyses of the tumor and healthy skin are reported.Results:Abrupt changes in architectures of the dermal and epidermal layers in the GCT lesion were observed. These architectural changes were not observed in healthy skin.Discussion:To quantitatively differentiate healthy skin from tumor regions, an optical attenuation coefficient analysis b...

【 授权许可】

CC BY