New Insights Regarding Genetic Aspects of Childhood Obesity: A Minireview

Frontiers in Pediatrics

Cristina Oana Mǎrginean¹ 

关键词: obesity;    genetics;    children;    etiology;    dietary interventions;   

DOI  :  10.3389/fped.2018.00271

学科分类：儿科学

来源: Frontiers

【 摘 要 】

Introduction: Childhood obesity is occurring at alarming rates in both developed and developing countries. “Obesogenic” environmental factors must be associated with variants of different risk alleles to determine polygenic or common obesity, and their impact depends on different developmental stages.The interaction between obesogenic environment and genetic susceptibility results in the so-called polygenic forms of obesity. In contrast, monogenic and syndromic obesity are not influenced by environmental events. Therefore, this review aimed to underline the roles of some of the most studied genes in the development of monogenic and polygenic obesity in children.

【 授权许可】

CC BY