Efficacy of 18F-fluorodeoxyglucose PET/CT for Detecting Lymph Node Metastasis in Papillary Thyroid Carcinoma:

OTO Open

Dong WonLee¹ 

关键词: positron emission tomography;    fluorodeoxyglucose F18;    ultrasonography;    computed tomography;    lymph node;    papillary thyroid carcinoma;   

DOI  :  10.1177/2473974X18788545

学科分类：外科医学

来源: Sage Journals

【 摘 要 】

ObjectiveTo evaluate the efficacy of preoperative 18F-fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) for detecting cervical lymph node (LN) metastasis in papillary thyroid carcinoma (PTC).Study DesignCase series with chart review.SettingUniversity tertiary care facility.Subjects and MethodsWe retrospectively compared the pathologic results for 409 cervical LN levels in 140 patients who underwent thyroidectomy and central neck dissection with/without lateral neck dissection with the findings of preoperative PET/CT, ultrasonography (US), and CT. We judged LN metastasis in PET/CT using the maximum standardized uptake value (SUVmax) at the optimal cutoff value in receiver operating characteristic curves and compared the sensitivity, specificity, and diagnostic accuracy of the 3 imaging tools.ResultsAt all neck levels (central and lateral compartments), PET/CT had a sensitivity of 57.5%, specificity of 68.6%, and diagnostic accuracy of 63.6% when the cutoff value of SUVmax was 1.1...

【 授权许可】

CC BY-NC