Left Ventricular Function Evaluation on a 3T MR Scanner with Parallel RF Transmission Technique: Prospective Comparison of Cine Sequences Acquired before and after Gadolinium Injection

PLoS One

Thibault Caspar¹  Mickaël Schaeffer²  Mi-Young Jeung³  Anthony Schultz³  Aïssam Labani³  Mickaël Ohana³  Soraya El Ghannudi³  Paul Thomas Jurgens⁴  Catherine Roy⁵ 

[1] Cardiology Department, Nouvel Hôpital Civil, Strasbourg University Hospital, Strasbourg, France;Public Health and Biostatistics Department, Nouvel Hôpital Civil, Strasbourg University Hospital, Strasbourg, France;Radiology Department, Nouvel Hôpital Civil, Strasbourg University Hospital, Strasbourg, France;University of Colorado, Denver, Colorado, United States of America;iCube Laboratory, Université de Strasbourg / CNRS, UMR 7357, 67400, Illkirch, France

关键词: Gadolinium;    Magnetic resonance imaging;    Image processing;    Myocardium;    Bayesian method;    Amperometry;    Cardiovascular imaging;    Ejection fraction;   

DOI  :  10.1371/journal.pone.0163503

学科分类：医学（综合）

来源: Public Library of Science

【 摘 要 】

Objectives To compare cine MR b-TFE sequences acquired before and after gadolinium injection, on a 3T scanner with a parallel RF transmission technique in order to potentially improve scanning time efficiency when evaluating LV function. Methods 25 consecutive patients scheduled for a cardiac MRI were prospectively included and had their b-TFE cine sequences acquired before and right after gadobutrol injection. Images were assessed qualitatively (overall image quality, LV edge sharpness, artifacts and LV wall motion) and quantitatively with measurement of LVEF, LV mass, and telediastolic volume and contrast-to-noise ratio (CNR) between the myocardium and the cardiac chamber. Statistical analysis was conducted using a Bayesian paradigm. Results No difference was found before or after injection for the LVEF, LV mass and telediastolic volume evaluations. Overall image quality and CNR were significantly lower after injection (estimated coefficient cine after > cine before gadolinium: -1.75 CI = [-3.78;-0.0305], prob(coef>0) = 0% and -0.23 CI = [-0.49;0.04], prob(coef>0) = 4%) respectively), but this decrease did not affect the visual assessment of LV wall motion (cine after > cine before gadolinium: -1.46 CI = [-4.72;1.13], prob(coef>0) = 15%). Conclusions In 3T cardiac MRI acquired with parallel RF transmission technique, qualitative and quantitative assessment of LV function can reliably be performed with cine sequences acquired after gadolinium injection, despite a significant decrease in the CNR and the overall image quality.

【 授权许可】

CC BY