期刊论文详细信息
Frontiers in Pediatrics | |
High-Resolution Melting Curve Analysis, a Rapid and Affordable Method for Mutation Analysis in Childhood Acute Myeloid Leukemia | |
Yin Liu1  | |
关键词: FLT3; NPM1; MLL; high-resolution melting curve analysis; acute myeloid leukemia; childhood; | |
DOI : 10.3389/fped.2014.00096 | |
学科分类:儿科学 | |
来源: Frontiers | |
【 摘 要 】
Background: Molecular genetic alterations with prognostic significance have been described in childhood acute myeloid leukemia (AML). The aim of this study was to establish cost-effective techniques to detect mutations of FMS-like tyrosine kinase 3 (FLT3), nucleophosmin 1 (NPM1), and a partial tandem duplication within the mixed-lineage leukemia (MLL-PTD) genes in childhood AML.
【 授权许可】
CC BY
【 预 览 】
Files | Size | Format | View |
---|---|---|---|
RO201904021953901ZK.pdf | 686KB | download |