Effect of exercise training on clot strength in patients with peripheral artery disease and intermittent claudication: An ancillary study:

SAGE Open Medicine

KarinMauer¹ 

关键词: Peripheral artery disease;    clot strength;    exercise training;   

DOI  :  10.1177/2050312115575938

学科分类：医学（综合）

来源: Sage Journals

【 摘 要 】

Objectives:Patients with peripheral artery disease have walking impairment, greater thrombotic risk, and are often treated with exercise training. We sought to determine the effect of a 3-month-long exercise program on clot strength among patients with peripheral artery disease and intermittent claudication.Methods:Twenty-three symptomatic peripheral artery disease patients were randomly assigned to a walking exercise program or to an attention control group who performed light resistance exercise. We investigated the effect of exercise training on clot strength and time to clot formation was assessed by thromboelastography.Results:After 3 months of exercise, clot strength (maximal amplitude) and time to clot formation (R) did not change significantly from baseline, even after improvements in claudication onset time (p < 0.01) and peak walking time (p < 0.05). Furthermore, changes in clot formation parameters were not significantly different between groups. Among the 10 individuals demonstrating a reducti...

【 授权许可】

CC BY