Atypical White Matter Connectivity in Dyslexic Readers of a Fairly Transparent Orthography

Frontiers in Psychology

Gojko Žarić¹ 

关键词: developmental dyslexia;    structural connectivity;    diffusion tensor imaging;    reading network;    anterior thalamic radiation;    arcuate fasciculus;   

DOI  :  10.3389/fpsyg.2018.01147

学科分类：心理学（综合）

来源: Frontiers

【 摘 要 】

Atypical structural properties of the brain’s white matter bundles have been associated with failing reading acquisition in developmental dyslexia. Because these white matter properties may show dynamic changes with age and orthographic depth, we examined fractional anisotropy (FA) along 16 white matter tracts in 8- to 11-year-old dyslexic (DR) and typically reading (TR) children learning to read in a fairly transparent orthography (Dutch). Our results showed higher FA values in the bilateral anterior thalamic radiations of DRs and FA values of the left thalamic radiation scaled with behavioral reading-related scores. Furthermore, DRs tended to have atypical FA values in the bilateral arcuate fasciculi. Children’s age additionally predicted FA values along the tracts. Together, our findings suggest differential contributions of cortical and thalamo-cortical pathways to the developing reading network in dyslexic and typical readers, possibly indicating prolonged letter-by-letter reading or increased attentional and/or working memory demands in dyslexic children during reading.

【 授权许可】

CC BY