The Present and Future of Biomarkers in Prostate Cancer: Proteomics, Genomics, and Immunology Advancements: Supplementary Issue: Biomarkers and their Essential Role in the Development of Personalised Therapies (A)

Biomarkers in Cancer

Pierre-OlivierGaudreau¹ 

关键词: prostate cancer;    biomarker;    genomics;    proteomics;    immunology;   

DOI  :  10.4137/BIC.S31802

学科分类：医学（综合）

来源: Sage Journals

【 摘 要 】

Prostate cancer (PC) is the second most common form of cancer in men worldwide. Biomarkers have emerged as essential tools for treatment and assessment since the variability of disease behavior, the cost and diversity of treatments, and the related impairment of quality of life have given rise to a need for a personalized approach. High-throughput technology platforms in proteomics and genomics have accelerated the development of biomarkers. Furthermore, recent successes of several new agents in PC, including immunotherapy, have stimulated the search for predictors of response and resistance and have improved the understanding of the biological mechanisms at work. This review provides an overview of currently established biomarkers in PC, as well as a selection of the most promising biomarkers within these particular fields of development.

【 授权许可】

CC BY