Association of Serum Adiponectin Levels with Metabolic Syndrome Risk Factors in Malay Adults

World Nutrition Journal

Nur Firdaus Isa¹  Hamid Jan B. Jan Mohamed²  Wan Manan Wan Muda²  Laila Ruwaida Mohd Zainuddin³ 

[1] Kulliyyah of Science, IIUM;Universiti Sains Malaysia;Universiti Sultan Zainal Abidin (UniSZA),

关键词: adipokines;    metabolic syndrome;    obesity;    dyslipidaemia;    Asian;   

DOI  :  10.25220/WNJ.V01i1.0005

学科分类：卫生学

来源: Indonesian Nutrition Association

【 摘 要 】

Introduction:This study aimed to investigate the relationship between serum adiponectin and metabolic syndrome in adults living in rural Malaysia. Methods:A total of 299 Malay adults (men=124; women = 175) with a mean age 48.8 (11.7) years were recruited. Measurements for waist circumference and blood pressure were taken before drawing an overnight fasting blood samples. Biochemical tests for triglycerides, HDL cholesterol, glucose and serum adiponectin concentration were measured. Results:Our results show that the adiponectin level in the subjects with metabolic syndrome was significantly lower than those without metabolic syndrome ( p< 0.05). Among the metabolic syndrome risk factors, adiponectin level was significantly associated with hypertriglyceridemia and reduced HDL cholesterol ( p< 0.001). Conclusion:The outcome from this study which highlights the association of hypoadiponectinemia with risk factors of metabolic syndrome in Malay adults, suggests that the reduced level of adiponectin may play a pivotal role in the development of metabolic syndrome in this ethnic group.

【 授权许可】

CC BY-NC-SA