Foot & Ankle Orthopaedics | |
Matrix-associated Stem Cell Transplantation (MAST) in Chondral Lesions at the Ankle as Part of a Complex Surgical Approach: Five-year Follow-up in 100 Patients | |
MartinusRichter1  | |
关键词: Chondral lesion; Stem cell; Collagen matrix; Matrix-associated stem cell transplantation (MAST); Ankle; | |
DOI : 10.1177/2473011418S00404 | |
学科分类:医学(综合) | |
来源: Sage Journals | |
【 摘 要 】
Category:AnkleIntroduction/Purpose:The aim of the study was to assess the 5-year-follow-up after matrix-associated stem cell transplantation (MAST) in chondral lesions at the ankle as part of a complex surgical approach.Methods:In a prospective consecutive non-controlled clinical follow-up study, all patients with chondral defect that were treated with MAST from April1 2009 to September 30, 2011 were analyzed. Size and location of the chondral defects and the Visual-Analogue-Scale Foot and Ankle (VAS FA) before treatment and at follow-up were analysed. Stem cell-rich blood was harvested during the procedure from the ipsilateral pelvic bone marrow with a Jamshidi needle (10 x 3 mm, Cardinal, Dublin, OH, USA) and a special syringe (Arthrex-ACP, Arthrex, Naples, FL, USA) through a stab incision. The syringe was centrifuged (10 minutes, 1,500 rotations per minute). The supernatant was used to impregnate a collagen I/III matrix (Chondro-Gide, Geistlich, Wollhusen, Switzerland) that was cut to the size of the c...
【 授权许可】
CC BY
【 预 览 】
Files | Size | Format | View |
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RO201904020020536ZK.pdf | 190KB | download |