Common variants in adiponectin gene are associated with coronary artery disease and angiographical severity of coronary atherosclerosis in type 2 diabetes

卷:12

Tong, Guoxin ; Wang, Ningfu ; Leng, Jianhang ; Tong, Xiaoshan ; Shen, Yun ; Yang, Jianmin ; Ye, Xianhua ; Zhou, Liang ; Zhou, Yujie

关键词: Adiponectin;    Genetics;    Coronary artery disease;    Angiography;    Gensini score;    Sullivan Extent score;    Single nucleotide polymorphism;   

DOI  :  10.1186/1475-2840-12-67

学科分类：内分泌与代谢学

【 摘 要 】

Background: Adiponectin, an adipokine facilitating insulin action, has antiatherogenic effects. This study investigated whether common single nucleotide polymorphisms (SNPs) in the adiponectin gene influenced plasma adiponectin level and whether they were