Determination of chlorophenols in honey samples using in-situ ionic liquid-dispersive liquid-liquid microextraction as a pretreatment method followed by high-performance liquid chromatography

卷:174

Fan, Chen ; Li, Nai ; Cao, Xueli

关键词: Chlorophenols;    Honey;    High-performance liquid chromatography (HPLC);    In-situ ionic liquid-dispersive liquid-liquid microextraction (IL-DLLME);    Pretreatment;   

DOI  :  10.1016/j.foodchem.2014.11.050

学科分类：食品科学和技术

【 摘 要 】

In-situ ionic liquid-dispersive liquid-liquid microextraction (IL-DLLME) method was developed as a pretreatment method for the detection of six chlorophenols (CPs) in honey samples. The hydrophobic ionic liquid [C4MIM][NTf2], formed in-situ by the hydrophilic ionic liquid [C4MIM][BF4] and the ion exchange reagent LiNTf2 was used as the microextractant solvent of CPs from honey sample. Then the enriched analytes were back-extracted into 40 mu L. of 0.14 M NaOH solution and finally subjected to analysis by high-performance liquid chromatography. The method showed low limit of detection of CPs, 0.8-3.2 mu g/L and high enrichment factor, 34-65 with the recoveries range from 91.60% to 114.33%. The method is simple, rapid, environmentally friendly and with high extraction efficiency. (C) 2014 The Authors. Published by Elsevier Ltd.