Low Glycemic Index Prototype Isomaltulose-Update of Clinical Trials

卷:9

Maresch, Constanze Christin ; Petry, Sebastian Friedrich ; Theis, Stephan ; Bosy-Westphal, Anja ; Linn, Thomas

Justus Liebig Univ

关键词: glycemic index;    isomaltulose;    glucose metabolism;    diabetes mellitus;    weight-loss maintenance;    clinical trials;    fertility and pregnancy outcome;    sweetened beverages;   

DOI  :  10.3390/nu9040381

学科分类：食品科学和技术

【 摘 要 】

Low glycemic index diets are supposed to achieve a more beneficial effect on blood glucose control in people with diabetes mellitus and may also provide metabolic benefits for the general population. A prototype of a low-glycemic index carbohydrate is the natural occurring disaccharide isomaltulose that can be commercially produced from sucrose (beet sugar) to industrial scale. It is currently used in various food and drink applications as well as special and clinical nutrition feeds and formula diet as a food ingredient and alternative sugar. Here we provide an overview on clinical trials with isomaltulose including an analysis of its effects on glycemia and fat oxidation as compared to high glycemic index sugars and carbohydrates. In addition, we discuss recent reports on beneficial effects in weight-loss maintenance and pregnancy.